BioStacks
Source Naturals

L-Tryptophan 500 mg

Powder · 0.5 Gram · 66 servings

iHerbAmazon

Best for

Sleep

Ingredients (1)

L-Tryptophan

100%

Dose

1000 mg

Target

250–1000 mg

Form

—

Other Ingredients

No other ingredients listed

How to Take It

Best taken in the evening

Take at night. Other amino acids compete for brain uptake, so a protein-heavy meal blunts it.

On an empty stomach
Keep it away from protein-heavy meals
Space it a couple of hours from SAMe
Do not combine with St. John's Wort

Each of these raises serotonin activity on top of St. John's Wort, and together they can trigger serotonin syndrome — agitation, rapid heartbeat, raised blood pressure. Not without medical supervision.

General guidance based on the ingredients, not a substitute for the label or your doctor.

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Sources & Scoring

Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).

This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.

The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.

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