BioStacks
Source Naturals

Serene Science 5-HTP 50 mg

1 Capsule · 30 servings · $0.31/serving

iHerbAmazon

Best for

Sleep

Ingredients (1)

5-HTP

100%

Dose

100 mg

Target

100–300 mg

Form

—

Other Ingredients (4)

Magnesium StearateLubricant

A salt of stearic acid used as a lubricant in tablet and capsule production

Silicon DioxideAnti-caking

Fine silica powder used to prevent clumping

GelatinCapsule

Protein derived from collagen, used in traditional capsule shells

Microcrystalline CelluloseBinder

Plant-derived cellulose used as a binder and filler in supplements

How to Take It

Best taken in the evening

Take in the evening. Amino acids compete for the same transport into the brain, so a protein-heavy meal blunts it.

On an empty stomach
Keep it away from protein-heavy meals
Space it a couple of hours from SAMe

On the label

1 to 2 capsules once or twice daily with meals, or as directed by your healthcare professional.

Labels usually say “with food” because it's gentler on the stomach, not because it absorbs better. Fasted absorbs more — start there, and switch to a light meal if it bothers you.

Do not combine with St. John's Wort

Each of these raises serotonin activity on top of St. John's Wort, and together they can trigger serotonin syndrome — agitation, rapid heartbeat, raised blood pressure. Not without medical supervision.

General guidance based on the ingredients, not a substitute for the label or your doctor.

Price Check

$9.44

$10$20$50

Cheaper than 92% of 54 5-HTP supplements

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Sources & Scoring

Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).

This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.

The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.

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