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What it does
A combination of 2 label ingredients.
Deglycyrrhizinated Licorice (DGL) root extract
Form not confirmedGrade —
Studied for digestive symptoms, but benefits remain uncertain; glycyrrhizin-containing licorice can cause serious heart-related side effects.
Glycine
Form not confirmedGrade —
Small studies suggest improved sleep in adults with sleep complaints; evidence is limited and at high risk of bias.
Ingredients (2)
Other ingredients
ErythritolSweetener
Witkowski et al. 2023 (Nature Medicine, PMID 36849732) reported elevated plasma erythritol associated with major adverse cardiovascular events (MACE) in two cohorts (n=4,000+), with in-vitro and ex-vivo evidence of enhanced platelet aggregation. Replication is ongoing; FDA and EFSA have not changed their safety positions, but the signal is real and the additive is purely cosmetic. Better-established concern: GI tolerance — single doses above ~50 g cause osmotic diarrhea. Lower threshold for children.
MaltodextrinBinder
Spikes blood sugar faster than table sugar (glycemic index 85–105). Research links it to gut bacteria changes that may promote intestinal inflammation (Nickerson et al. 2015). Used as a cheap filler — adds nothing beneficial.
XylitolSweetener
A FODMAP sugar alcohol that can cause GI distress (bloating, gas, diarrhea) at moderate doses (>10-20g/day), though supplement amounts are typically small. Extremely toxic to dogs — households with pets should store securely.
Peppermint OilFlavor
Essential oil distilled from peppermint (Mentha piperita) leaves.
Silicon DioxideAnti-caking
Fine silica powder used to prevent clumping
Calcium CarbonateBuffer
Common calcium salt used as a buffering agent, filler, or mineral fortification in supplements
HypromelloseCapsule
Plant-derived capsule material from cellulose
Stevia ExtractSweetener
Zero-calorie natural sweetener extracted from the leaves of Stevia rebaudiana
Lab testing
How to take it
With or without food
On the label
Chew 2 tablets daily.
Price check
$13.96
$0.16 / serving
Near the median of 20 licorice root extract supplements
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Sources & Scoring
Nutrient data (RDA, UL, and safety thresholds) sourced from the NIH Office of Dietary Supplements and the National Academies Dietary Reference Intakes (DRI).
This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.
The score analyzes what's on the label: ingredient doses vs. studied ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.
Not medical advice. Consult your healthcare professional.