Each serving delivers 1g of **Glycine**, but the clinical research on sleep quality used 3g before bedtime — so you'd need to take all six capsules (three servings) to reach the studied dose. At that intake, you're right at the effective minimum for supporting sleep onset and reducing next-day fatigue.

**Glycine** also serves as a building block for collagen and plays a role in creatine synthesis, giving this product relevance for skin and muscle support beyond sleep. The capsule form makes dosing flexible, which helps since individual needs vary.

The main tradeoff is pill burden. Getting to the 3g clinical dose means six capsules per night, which makes a powder format more practical for most people at this dose level.

BioStacks
Thorne

Glycine

2 Capsules · 125 servings · $0.25/serving

iHerbAmazon

Every active here is dosed below the amount studied to work. See how each one compares in the breakdown below.

Best for

Sleep

Ingredients (1)

Glycine

33%

Dose

1 Gram(s)

Target

3–5 g

Form

—

Other Ingredients (2)

Silicon DioxideAnti-caking

Fine silica powder used to prevent clumping

HypromelloseCapsule

Plant-derived capsule material from cellulose

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Sources & Scoring

Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).

This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.

The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.

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