Each serving delivers 1g of **Glycine**, but the clinical research on sleep quality used 3g before bedtime — so you'd need to take all six capsules (three servings) to reach the studied dose. At that intake, you're right at the effective minimum for supporting sleep onset and reducing next-day fatigue.

**Glycine** also serves as a building block for collagen and plays a role in creatine synthesis, giving this product relevance for skin and muscle support beyond sleep. The capsule form makes dosing flexible, which helps since individual needs vary.

The main tradeoff is pill burden. Getting to the 3g clinical dose means six capsules per night, which makes a powder format more practical for most people at this dose level.

BioStacks
Thorne

Glycine

2 Capsules · 125 servings

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Every active here is dosed below the amount studied to work. See how each one compares in the breakdown below.

What it does

Glycine

Form not confirmedGrade —

Small studies suggest improved sleep in adults with sleep complaints; evidence is limited and at high risk of bias.

Sleep
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Ingredients (1)

Other ingredients

Silicon DioxideAnti-caking

Fine silica powder used to prevent clumping

HypromelloseCapsule

Plant-derived capsule material from cellulose

Lab testing

How to take it

With or without food

On the label

Suggested use: Take 2 capsules one to three times daily or as recommended by your health-care practitioner.

Price check

$31.00

$10$20$50

Near the median of 46 glycine supplements

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Sources & Scoring

Nutrient data (RDA, UL, and safety thresholds) sourced from the NIH Office of Dietary Supplements and the National Academies Dietary Reference Intakes (DRI).

This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.

The score analyzes what's on the label: ingredient doses vs. studied ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.

Not medical advice. Consult your healthcare professional.

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