Thorne S.A.T. is a liver-focused formula built around three ingredients in high-absorption phytosome forms. **Siliphos** delivers silybin — the active compound in milk thistle — in a form that absorbs roughly 10x better than standard extracts. At the recommended two capsules daily, you're getting 300mg, just under the 360mg clinical minimum; taking three capsules puts you squarely in the studied range for supporting liver enzymes and protecting liver cells.

**Meriva curcumin** adds anti-inflammatory support at 300–450mg across two to three capsules, comfortably within its effective phytosome dose range. **Artichoke leaf extract** at the same dose lands right at the clinical minimum for stimulating bile flow and supporting digestion.

The main consideration is capsule count — you'll want three daily to get all three ingredients into their full clinical ranges, which means a 60-capsule bottle lasts just 20 days.

BioStacks
Thorne

S.A.T.

1 Capsule × 2/day · 60 servings · $0.78/serving

iHerbAmazon

Best for

Liver

Ingredients (3)

Meriva

100%

Dose/day

300 mg

Target

200–400 mg

Form

Premium

Artichoke Leaf Extract

100%

Dose/day

300 mg

Target

300–640 mg

Form

—

Siliphos

83%

Dose/day

300 mg

Target

360–1080 mg

Form

Premium

Other Ingredients (4)

Silicon DioxideAnti-caking

Fine silica powder used to prevent clumping

HypromelloseCapsule

Plant-derived capsule material from cellulose

LeucineFlow Aid

Branched-chain amino acid used as a processing aid

Microcrystalline CelluloseBinder

Plant-derived cellulose used as a binder and filler in supplements

How to Take It

Take it anytime

Meriva is a phytosome — the carrier does much of the absorption work, so it's less dependent on dietary fat than plain curcumin. Its trials still dosed it with meals.

With or without food
Split into 2 doses across the day

On the label

Suggested use: Take 1 capsule two to three times daily or as recommended by your health-care practitioner.

General guidance based on the ingredients, not a substitute for the label or your doctor.

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Sources & Scoring

Nutrient data (RDA, UL, and safety thresholds) sourced from the NIH Office of Dietary Supplements and the National Academies Dietary Reference Intakes (DRI).

This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.

The score analyzes what's on the label: ingredient doses vs. studied ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.

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