Thorne S.A.T. is a liver-focused formula built around three ingredients in high-absorption phytosome forms. **Siliphos** delivers silybin — the active compound in milk thistle — in a form that absorbs roughly 10x better than standard extracts. At the recommended two capsules daily, you're getting 300mg, just under the 360mg clinical minimum; taking three capsules puts you squarely in the studied range for supporting liver enzymes and protecting liver cells.

**Meriva curcumin** adds anti-inflammatory support at 300–450mg across two to three capsules, comfortably within its effective phytosome dose range. **Artichoke leaf extract** at the same dose lands right at the clinical minimum for stimulating bile flow and supporting digestion.

The main consideration is capsule count — you'll want three daily to get all three ingredients into their full clinical ranges, which means a 60-capsule bottle lasts just 20 days.