Interaction checker

Can you take 5-HTP with Vitamin B6?

5-HTP + Vitamin B6

Vitamin B6 (as P5P) is a required cofactor for aromatic amino acid decarboxylase, the enzyme that converts 5-HTP to serotonin. Without adequate B6, 5-HTP→serotonin conversion is impaired.

Supplement-to-supplement only. For interactions with prescription medications, talk to your doctor or pharmacist.

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5-HTPVitamin B6
5-HTP + Vitamin B6

Vitamin B6 (as P5P) is a required cofactor for aromatic amino acid decarboxylase, the enzyme that converts 5-HTP to serotonin. Without adequate B6, 5-HTP→serotonin conversion is impaired.

Do 5-HTP and Vitamin B6 actually work at your doses?

BioStacks scores supplements on clinical efficacy — real doses vs. the research. Scan a bottle and see.