Interaction checker
Can you take St. John's Wort with 5-HTP?
St. John's Wort + 5-HTP — Serotonin Riskhigh
Both increase serotonergic activity. Combining them raises the risk of serotonin syndrome (agitation, rapid heartbeat, high blood pressure). Do not combine without medical supervision.
Supplement-to-supplement only. For interactions with prescription medications, talk to your doctor or pharmacist.
Add more to your stack
St. John's Wort5-HTP
St. John's Wort + 5-HTP — Serotonin Riskhigh
Both increase serotonergic activity. Combining them raises the risk of serotonin syndrome (agitation, rapid heartbeat, high blood pressure). Do not combine without medical supervision.
Do St. John's Wort and 5-HTP actually work at your doses?
BioStacks scores supplements on clinical efficacy — real doses vs. the research. Scan a bottle and see.