Best for Liver
Best Artichoke for Liver
Top 9 products ranked · Reviewed May 2026 · 300–640 mg clinical dose
Why Artichoke for Liver
Artichoke plays a supporting role in liver. Artichoke leaf extract contains cynarin and chlorogenic acid, which stimulate bile production and support fat digestion. Multiple clinical trials and a Cochrane review support its use for functional dyspepsia (indigestion) and mild cholesterol reduction. In clinical studies, artichoke stimulates bile production for improved fat digestion and liver detox.
What dose to look for
Clinical studies typically use 300–640 mg of artichoke. Most clinical studies use 300–640 mg/day of standardized leaf extract. Higher doses (up to 1800 mg) used in dyspepsia and cholesterol studies. Typically standardized to cynarin and chlorogenic acid content. Products below this range may not deliver meaningful results.
What the research says
Artichoke has moderate clinical evidence for liver benefits. Multiple clinical trials and a Cochrane review support its use for indigestion and mild cholesterol reduction Learn more
Clinical research on Artichoke (Cynara scolymus)
MODERATE — Several RCTs for liver enzymes and cholesterol · 600–2,400 mg/day (leaf extract)
- •2018 meta-analysis of 9 RCTs found artichoke leaf extract significantly reduced total cholesterol, LDL, and triglycerides. Several trials also showed reduced ALT levels. PubMed
- •2018 RCT (90 patients with NAFLD) showed 600 mg/day artichoke extract for 2 months significantly reduced ALT, AST, and total bilirubin levels vs placebo. PubMed
- •Active compounds (cynarin, luteolin, chlorogenic acid) stimulate bile production (choleretic effect) and protect hepatocytes from oxidative damage. Traditional use in European phytotherapy is well-documented.