BioStacksBest NAD+ Precursor (NR) for Longevity
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Clinical dose: 250–1000 mg
Why NAD+ Precursor (NR) for Longevity
When it comes to longevity, NAD+ Precursor (NR) is one of the most important nutrients to consider. NR is a form of vitamin B3 and a precursor to NAD+, a coenzyme essential for energy metabolism, DNA repair, and sirtuin activation. NAD+ levels decline ~42% between ages 30–70. NR dose-dependently raises blood NAD+ (22–142% at 100–1000 mg/day).
What dose to look for
Clinical studies typically use 250–1000 mg of nad+ precursor (nr). Most human studies use 250–1000 mg/day. 300 mg is the most common consumer dose. Clinical trials typically use 1000 mg/day (500 mg twice daily). Supplements that fall short of this threshold are unlikely to match what clinical trials achieved.
The evidence behind nad+ precursor (nr)
Research supporting nad+ precursor (nr) for longevity is rated as moderate. Several human trials confirm it raises NAD+ levels dose-dependently, but health outcomes still emerging Learn more
