About D-Chiro-Inositol
A minor inositol isomer involved in insulin signaling. Most commonly studied alongside Myo-Inositol for PCOS at a 40:1 ratio. Well tolerated at typical doses. No established RDA/UL.
What D-Chiro-Inositol supports
- May support hormonal balance in PCOS (with Myo-Inositol)
- Involved in insulin signaling pathways
How much D-Chiro-Inositol to take
The RDA prevents deficiency. The effective range is what clinical trials used to actually move the outcome.
Effective
25–100
mg
Typical D-Chiro-Inositol dose; often paired with Myo-Inositol in a 40:1 ratio (e.g. 2000 mg Myo : 50 mg DCI).
Clinical evidence
Moderate clinical evidence. A few trials support its use alongside myo-inositol for PCOS at a 40:1 ratio
NIH Fact Sheet