About Saffron
Saffron extract (Crocus sativus) standardized to safranal and crocins shows moderate-to-large effect sizes for depression and anxiety symptoms in meta-analyses of RCTs. Some trials show non-inferiority to SSRIs. Also modulates cortisol response under stress. Standard dose is 30mg/day.
What Saffron supports
- Supports positive mood (multiple RCTs)
- May reduce anxiety symptoms
- Modulates cortisol stress response
How much Saffron to take
Clinical studies typically use 28–30 mg of Saffron. Most RCTs use 30mg/day standardized extract (e.g. affron®). Meta-analyses confirm efficacy at this dose for mood and anxiety.
- Effective range
- 28–30 mg
Clinical evidence
Moderate clinical evidence. Meta-analyses of multiple clinical trials show moderate-to-large effect sizes for mood and anxiety
Examine.com