BioStacksBest Saffron for Stress & Mood
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Clinical dose: 28–30 mg
Saffron and stress & mood
For stress & mood support, Saffron is a important ingredient backed by research. Saffron extract (Crocus sativus) standardized to safranal and crocins shows moderate-to-large effect sizes for depression and anxiety symptoms in meta-analyses of RCTs. Some trials show non-inferiority to SSRIs.
Effective dosing
Most evidence supports 28–30 mg of saffron daily. Most RCTs use 30mg/day standardized extract (e.g. affron®). Meta-analyses confirm efficacy at this dose for mood and anxiety. Products below this range may not deliver meaningful results.
What the research says
The clinical evidence for saffron in stress & mood is moderate. Meta-analyses of multiple clinical trials show moderate-to-large effect sizes for mood and anxiety Learn more
