BioStacks
Best for
Ingredients (6)
Chromax Chromium
100%Dose
200 mcg
Target
200–1000 mcg
Form
Premium
Berberine HCl
80%Dose
400 mg
Target
500–1500 mg
Form
Standard
Banaba Leaf Extract
100%Dose
50 mg
Target
32–500 mg
Form
—
5-HTP
100%Dose
100 mg
Target
100–300 mg
Form
—
Cayenne Fruit Extract
8%Dose
20 mg
Target
250–1000 mg
Form
—
Other Ingredients (4)
Magnesium StearateLubricant
A salt of stearic acid used as a lubricant in tablet and capsule production
Silicon DioxideAnti-caking
Fine silica powder used to prevent clumping
Microcrystalline CelluloseBinder
Plant-derived cellulose used as a binder and filler in supplements
HypromelloseCapsule
Plant-derived capsule material from cellulose
How to Take It
Best taken in the evening
Contains 5-HTP, so it belongs in the evening. What's in this is easier on the stomach taken with food.
With food
5-HTP does better on an empty stomach, but something else in this bottle needs food. Taking the whole product with a meal is the better trade — an upset stomach is why most people stop.
Keep it away from protein-heavy meals
Space it a couple of hours from SAMe
On the label
Take one serving (1 capsule) with 8-12 fl. oz. of water in the morning, and one serving (1 capsule) with 8-12 fl. oz. of water 5-6 hours later in the mid-afternoon. Once tolerance has been assessed, if you are looking for an additional boost of energy, an additional capsule may be taken with your first serving of the day. Do not take this product within 6 hours of bedtime. DO NOT EXCEED 3 CAPSULES PER DAY. USE ONLY AS DIRECTED.
The label says morning, but the 5-HTP in it makes evening the safer call.
Do not combine with St. John's Wort
Each of these raises serotonin activity on top of St. John's Wort, and together they can trigger serotonin syndrome — agitation, rapid heartbeat, raised blood pressure. Not without medical supervision.
General guidance based on the ingredients, not a substitute for the label or your doctor.
Price Check
$49.99
Near the median of 49 metabolism supplements
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Sources & Scoring
Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).
This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.
The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.