BioStacks
Ingredients (17)
Niacin
80%Dose
20 mg
Target
25–500 mg
Form
—
Pantothenic Acid
20%Dose
10 mg
Target
50–500 mg
Form
—
Vitamin B6
8%Dose
2 mg
Target
25–100 mg
Form
—
Biotin
30%Dose
300 mcg
Target
1000–5000 mcg
Form
—
Vitamin D3
40%Dose
400 IU
Target
1000–5000 IU
Form
Premium
Other Ingredients (11)
BHAPreservative
Potential carcinogen in animal studies; may cause allergic reactions; restricted in EU
Polysorbate 80Emulsifier
Chassaing et al. 2015 (Nature, PMID 25731162) tested polysorbate 80 directly and showed it thinned the gut mucus barrier, altered microbiota composition, and induced low-grade inflammation and metabolic syndrome in mice. The strongest human evidence is for a related emulsifier rather than polysorbate 80 itself: Chassaing 2022 (Gastroenterology, PMID 34774538) was a controlled human feeding RCT of carboxymethylcellulose (CMC) that found microbial encroachment into the mucus layer — polysorbate 80 has not been tested in an equivalent human trial. In vitro work (e.g. Roberts 2010) shows polysorbate 80 enhances bacterial translocation across intestinal epithelium, and observational data link overall dietary-emulsifier exposure to IBD risk. EFSA is mid re-evaluation of polysorbates (E432–E436). For a supplement excipient with purely cosmetic function (improving the look/texture of soft gels and liquids), the gut-barrier risk profile is unfavorable when safer alternatives (sunflower lecithin, MCT carriers, gum acacia) are widely available.
Calcium Disodium EDTAPreservative
Generally well tolerated at the low levels used as a preservative and poorly absorbed orally, which limits systemic risk. But EDTA is a non-selective chelator: at higher chronic intakes it can bind and deplete essential minerals (zinc, iron) and has caused GI upset. Acceptable at trace preservative levels, but worth avoiding when a product also delivers minerals that EDTA could sequester.
Sodium BenzoatePreservative
Benzene can form in presence of ascorbic acid plus metals/heat/light; may trigger reactions in sensitive individuals
SucroseSweetener
Added sugars and high glycemic load; dental caries risk
Grain Alcohol (ethanol)Solvent
Food-grade ethanol used as an extraction or carrier solvent.
Natural FlavorsFlavor
Broad regulatory category of flavor constituents derived from natural sources. Composition is proprietary and not disclosed — 'Natural Flavors' can include several hundred different compounds depending on the target flavor profile, including hexane-extracted constituents and proprietary carrier solvents. 'Natural' is a regulatory definition (21 CFR §101.22), not a safety guarantee.
Citric AcidAcidulant
Natural acid derived from citrus fruits
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Sources & Scoring
Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).
This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.
The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.