BioStacks
Best for
Ingredients (2)
St. John’s Wort aerial parts extract
100%Dose/day
999 mg
Target
600–1200 mg
Form
Not listed
Hypericins
0%Dose/day
2.7 mg
Target
600–1200 mg
Form
—
Other Ingredients (3)
MaltodextrinBinder
Spikes blood sugar faster than table sugar (glycemic index 85–105). Research links it to gut bacteria changes that may promote intestinal inflammation (Nickerson et al. 2015). Used as a cheap filler — adds nothing beneficial.
Rice HullsAnti-caking
Ground outer husk of rice grains used as a plant-based flow and anti-caking agent
PullulanCapsule
Polysaccharide produced by fungal fermentation, used as a vegan capsule material
How to Take It
Best taken in the morning
Take earlier in the day with food. Check the conflicts below — it interacts seriously with serotonergic compounds.
With food
Label directs 3 servings — keep one for the morning
On the label
Take 1 capsule 3 times daily between meals or as directed by your health care provider.
The label says to take it on an empty stomach. What's in this one sits better with food, and you give up little by taking it that way.
Do not combine with 5-HTP, SAMe or Tryptophan
Each of these raises serotonin activity on top of St. John's Wort, and together they can trigger serotonin syndrome — agitation, rapid heartbeat, raised blood pressure. Not without medical supervision.
General guidance based on the ingredients, not a substitute for the label or your doctor.
Price Check
$37.95
Pricier than 99% of 24 st. john's wort supplements
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Sources & Scoring
Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).
This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.
The score analyzes what's on the label: ingredient doses vs. studied ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.