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What it does
Glucosamine Sulfate
Form not confirmedGrade —
Label lists D-Glucosamine Hydrochloride (1000 mg). Benefit information is limited.
Ingredients (1)
Other ingredients
Polysorbate 80Emulsifier
Chassaing et al. 2015 (Nature, PMID 25731162) tested polysorbate 80 directly and showed it thinned the gut mucus barrier, altered microbiota composition, and induced low-grade inflammation and metabolic syndrome in mice. The strongest human evidence is for a related emulsifier rather than polysorbate 80 itself: Chassaing 2022 (Gastroenterology, PMID 34774538) was a controlled human feeding RCT of carboxymethylcellulose (CMC) that found microbial encroachment into the mucus layer — polysorbate 80 has not been tested in an equivalent human trial. In vitro work (e.g. Roberts 2010) shows polysorbate 80 enhances bacterial translocation across intestinal epithelium, and observational data link overall dietary-emulsifier exposure to IBD risk. EFSA is mid re-evaluation of polysorbates (E432–E436). For a supplement excipient with purely cosmetic function (improving the look/texture of soft gels and liquids), the gut-barrier risk profile is unfavorable when safer alternatives (sunflower lecithin, MCT carriers, gum acacia) are widely available.
Titanium DioxideColorant
Banned in the EU (2022) over concerns that its ultra-fine particles may damage DNA in gut cells. Still allowed in the US. Used only for white coloring — provides no health benefit.
Magnesium StearateLubricant
A salt of stearic acid used as a lubricant in tablet and capsule production
Polyethylene Glycol (Coating)Coating
A polyether polymer used as a tablet coating and plasticizer
Silicon DioxideAnti-caking
Fine silica powder used to prevent clumping
Carnauba WaxCoating
Hard plant wax from the carnauba palm used to glaze gummies and tablets
Croscarmellose SodiumDisintegrant
Cross-linked cellulose derivative used as a superdisintegrant
Vegetable OilCarrier
Edible oils used as carriers in softgels and as processing aids
Lab testing
How to take it
With food
Split into 2 doses across the day
On the label
As a dietary supplement, take one caplet twice daily.
Price check
$24.99
$0.28 / serving
Pricier than 74% of 54 glucosamine sulfate supplements
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Sources & Scoring
Nutrient data (RDA, UL, and safety thresholds) sourced from the NIH Office of Dietary Supplements and the National Academies Dietary Reference Intakes (DRI).
This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.
The score analyzes what's on the label: ingredient doses vs. studied ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.
Not medical advice. Consult your healthcare professional.