BioStacks
GNC

St. John's Wort Extract 300 mg

1 Capsule · 200 servings · $0.13/serving

iHerbAmazon

Best for

Stress & Mood

Ingredients (2)

St. John's Wort herb extract

50%

Dose

300 mg

Target

600–1200 mg

Form

Not listed

Hypericin

0%

Dose

0.9 mg

Target

600–1200 mg

Form

—

Other Ingredients (2)

Microcrystalline CelluloseBinder

Plant-derived cellulose used as a binder and filler in supplements

HypromelloseCapsule

Plant-derived capsule material from cellulose

How to Take It

Best taken in the morning

Take earlier in the day with food. Check the conflicts below — it interacts seriously with serotonergic compounds.

With food

On the label

As a dietary supplement, take one to three capsules daily.

Do not combine with 5-HTP, SAMe or Tryptophan

Each of these raises serotonin activity on top of St. John's Wort, and together they can trigger serotonin syndrome — agitation, rapid heartbeat, raised blood pressure. Not without medical supervision.

General guidance based on the ingredients, not a substitute for the label or your doctor.

Price Check

$26.95

$10$20

Pricier than 84% of 24 st. john's wort supplements

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Sources & Scoring

Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).

This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.

The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.

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