BioStacks
Host Defense

Mood

2 Capsules · 30 servings · $1.00/serving

iHerbAmazon

Best for

Stress & Mood

Ingredients (6)

L-Theanine

100%

Dose

100 mg

Target

100–250 mg

Form

—

Holy Basil aerial part extract

67%

Dose

200 mg

Target

300–600 mg

Form

—

Ashwagandha root

83%

Dose

250 mg

Target

300–600 mg

Form

Budget

5-HTP

50%

Dose

50 mg

Target

100–300 mg

Form

—

Reishi mycelium/fermented brown rice biomass

20%

Dose

200 mg

Target

1000–3000 mg

Form

—

Other Ingredients (1)

PullulanCapsule

Polysaccharide produced by fungal fermentation, used as a vegan capsule material

How to Take It

Best taken in the evening

Contains 5-HTP, so it belongs in the evening. Ashwagandha is easier on the stomach taken with food.

With food

5-HTP does better on an empty stomach, but something else in this bottle needs food. Taking the whole product with a meal is the better trade — an upset stomach is why most people stop.

Keep it away from protein-heavy meals
Space it a couple of hours from SAMe

On the label

As a dietary supplement, take 2 capsules once per day. Can be taken with food or on an empty stomach or as recommended by your healthcare professional.

Do not combine with St. John's Wort

Each of these raises serotonin activity on top of St. John's Wort, and together they can trigger serotonin syndrome — agitation, rapid heartbeat, raised blood pressure. Not without medical supervision.

General guidance based on the ingredients, not a substitute for the label or your doctor.

Price Check

$29.95

$10$20$50

Near the median of 118 theanine supplements

Track this supplement in your stack

Get personalized insights, interactions, and coverage recommendations.

Get Started Free

Similar Supplements

Organic Stress Support

plnt

Organic Stress Support

5
Superior Sleep

Doctor's Best

Superior Sleep

😴 for Sleep

61
Grateful Dead Gummies (Stay Mellow)

Host Defense

Grateful Dead Gummies (Stay Mellow)

🧠 for Brain

6
KSM-66 Ashwagandha 600 mg

Carlyle

KSM-66 Ashwagandha 600 mg

🧘 for Stress & Mood

84
KSM-66 Ashwagandha 600mg

Horbäach

KSM-66 Ashwagandha 600mg

🧘 for Stress & Mood

84

Sources & Scoring

Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).

This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.

The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.

BioStacks

Know exactly what's in your supplements.

Navigate

  • Home
  • App Store
  • Google Play

Resources

  • Contact & Support
  • Pricing
  • Terms of Service
  • Privacy Policy
  • Refund Policy

Explore

  • Health Areas
  • Best Supplements
  • Nutrients
  • All Supplements

Popular Picks

  • Best Magnesium for Sleep
  • Best Collagen for Skin
  • Best Creatine for Muscle
  • Best Vitamin D for Bone Health
  • Best Probiotics for Digestion
  • Best CoQ10 for Heart
© 2026 BioStacks. All rights reserved. Not medical advice.