This is everyday folate (vitamin B9) in its active form, and the real dose is smaller than the label's headline implies. The 667 mcg DFE on the front works out to about 400 mcg of actual **L-methylfolate**, since DFE units inflate the figure by roughly 1.7x. That puts you right at the standard maintenance and preconception dose, squarely inside the 400–800 mcg range used clinically.

Because it arrives as 5-MTHF, your body uses it directly without the MTHFR conversion step that limits how well 40–50% of people process folic acid, so this 400 mcg lands as fully usable folate. One tablet a day covers general folate needs, red blood cell formation, and the neural-tube support that matters most before and during early pregnancy. For a diagnosed deficiency or mood-specific goals you'd want a higher dose, but as a daily maintenance source this does exactly that.

BioStacks
Igennus Healthcare Nutrition

Pure L-Methylfolate 667 mcg DFE

1 Tablet · 180 servings · $0.08/serving

iHerbAmazon

Ingredients (1)

L-methylfolate

100%

Dose

667 mcg DFE

Target

400–800 mcg

Form

Premium

Other Ingredients (3)

Ascorbyl PalmitateAntioxidant

Fat-soluble form of vitamin C used as preservative

Dicalcium PhosphateBinder

Calcium and phosphorus compound used as binder

Microcrystalline CelluloseBinder

Plant-derived cellulose used as a binder and filler in supplements

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Sources & Scoring

Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).

This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.

The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.

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