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Life Extension

L-Tryptophan 500 mg

1 Capsule · 90 servings · $0.28/serving

iHerbAmazon

Best for

Sleep

Ingredients (1)

L-Tryptophan

100%

Dose

500 mg

Target

250–1000 mg

Form

—

Other Ingredients (4)

HypromelloseCapsule

Plant-derived capsule material from cellulose

Microcrystalline CelluloseBinder

Plant-derived cellulose used as a binder and filler in supplements

Stearic AcidLubricant

Saturated fatty acid used as tablet lubricant

Microcrystalline CelluloseBinder

Plant-derived cellulose used as a binder and filler in supplements

How to Take It

Best taken in the evening

Take at night. Other amino acids compete for brain uptake, so a protein-heavy meal blunts it.

On an empty stomach
Keep it away from protein-heavy meals
Space it a couple of hours from SAMe

On the label

Take one (1) capsule 1 to 3 times daily on an empty stomach, or as recommended by a healthcare practitioner. For maximum absorption, take with a small amount of carbohydrate, such as diluted juice. Best if taken separately from protein and amino acids.

Do not combine with St. John's Wort

Each of these raises serotonin activity on top of St. John's Wort, and together they can trigger serotonin syndrome — agitation, rapid heartbeat, raised blood pressure. Not without medical supervision.

General guidance based on the ingredients, not a substitute for the label or your doctor.

Price Check

$24.75

$10$20$50

Pricier than 70% of 18 tryptophan supplements

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Sources & Scoring

Nutrient data (RDA, UL, and safety thresholds) sourced from the NIH Office of Dietary Supplements and the National Academies Dietary Reference Intakes (DRI).

This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.

The score analyzes what's on the label: ingredient doses vs. studied ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.

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