Hair Growth with Lustriva

Chassaing et al. 2015 (Nature, PMID 25731162) tested polysorbate 80 directly and showed it thinned the gut mucus barrier, altered microbiota composition, and induced low-grade inflammation and metabolic syndrome in mice. The strongest human evidence is for a related emulsifier rather than polysorbate 80 itself: Chassaing 2022 (Gastroenterology, PMID 34774538) was a controlled human feeding RCT of carboxymethylcellulose (CMC) that found microbial encroachment into the mucus layer — polysorbate 80 has not been tested in an equivalent human trial. In vitro work (e.g. Roberts 2010) shows polysorbate 80 enhances bacterial translocation across intestinal epithelium, and observational data link overall dietary-emulsifier exposure to IBD risk. EFSA is mid re-evaluation of polysorbates (E432–E436). For a supplement excipient with purely cosmetic function (improving the look/texture of soft gels and liquids), the gut-barrier risk profile is unfavorable when safer alternatives (sunflower lecithin, MCT carriers, gum acacia) are widely available.

Insect-derived (not vegan/vegetarian) and a recognized cause of IgE-mediated allergic reactions, including documented anaphylaxis. The FDA mandated explicit 'carmine'/'cochineal extract' labeling in 2011 specifically because of these reactions. Not toxic to the general population, but a genuine allergen with no health benefit; plant pigments achieve the same color.

A FODMAP sugar alcohol that may trigger GI discomfort (bloating, gas) in individuals with IBS or sorbitol malabsorption, even at small amounts found in supplements. Avoided in low-FODMAP diets.

Fractionated oils rich in C8/C10 triglycerides used as neutral carrier or anti-sticking agent

Protein derived from collagen, used in traditional capsule shells

Sweet-tasting liquid used in soft capsules and liquids

Non-GMO, non-allergenic emulsifier derived from sunflower seeds