BioStacks
Nature Made

Hair, Skin, & Nails

Capsule · 1 Softgel · 120 servings

iHerbAmazon

Best for

Immune

Ingredients (5)

Biotin

100%

Dose

2500 mcg

Target

1000–5000 mcg

Form

—

Vitamin A

100%

Dose

757.6 mcg

Target

700–1500 mcg

Form

Budget

Vitamin C

40%

Dose

100 mg

Target

250–2000 mg

Form

Budget

Copper

90%

Dose

900 mcg

Target

1000–2000 mcg

Form

Budget

Zinc

73%

Dose

11 mg

Target

15–30 mg

Form

Budget

Other Ingredients (9)

Polysorbate 80Emulsifier

Chassaing et al. 2015 (Nature, PMID 25731162) tested polysorbate 80 directly and showed it thinned the gut mucus barrier, altered microbiota composition, and induced low-grade inflammation and metabolic syndrome in mice. The strongest human evidence is for a related emulsifier rather than polysorbate 80 itself: Chassaing 2022 (Gastroenterology, PMID 34774538) was a controlled human feeding RCT of carboxymethylcellulose (CMC) that found microbial encroachment into the mucus layer — polysorbate 80 has not been tested in an equivalent human trial. In vitro work (e.g. Roberts 2010) shows polysorbate 80 enhances bacterial translocation across intestinal epithelium, and observational data link overall dietary-emulsifier exposure to IBD risk. EFSA is mid re-evaluation of polysorbates (E432–E436). For a supplement excipient with purely cosmetic function (improving the look/texture of soft gels and liquids), the gut-barrier risk profile is unfavorable when safer alternatives (sunflower lecithin, MCT carriers, gum acacia) are widely available.

Medium Chain Triglyceride OilCarrier

Fractionated oils rich in C8/C10 triglycerides used as neutral carrier or anti-sticking agent

Soy LecithinEmulsifier

Widely used emulsifier derived from soybeans

Calcium CarbonateBuffer

Common calcium salt used as a buffering agent, filler, or mineral fortification in supplements

GelatinCapsule

Protein derived from collagen, used in traditional capsule shells

GlycerinHumectant

Sweet-tasting liquid used in soft capsules and liquids

Vegetable OilCarrier

Edible oils used as carriers in softgels and as processing aids

Purified WaterSolvent

Water meeting USP specifications used as solvent/vehicle in gummies and liquids

How to Take It

Take it anytime

Take it with a meal containing fat — the vitamin A in it absorbs poorly without one.

With a meal containing fat
Space it a couple of hours from Iron and Calcium

On the label

Suggested use: Take 1 softgel daily with a meal. For easier swallowing, take with water before and during ingestion.

General guidance based on the ingredients, not a substitute for the label or your doctor.

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Sources & Scoring

Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).

This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.

The score analyzes what's on the label: ingredient doses vs. studied ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.

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