BioStacks
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Ingredients (1)
Magnesium
100%Dose
250 mg
Target
100–400 mg
Form
Budget
Other Ingredients (9)
Polysorbate 80Emulsifier
Chassaing et al. 2015 (Nature, PMID 25731162) tested polysorbate 80 directly and showed it thinned the gut mucus barrier, altered microbiota composition, and induced low-grade inflammation and metabolic syndrome in mice. The strongest human evidence is for a related emulsifier rather than polysorbate 80 itself: Chassaing 2022 (Gastroenterology, PMID 34774538) was a controlled human feeding RCT of carboxymethylcellulose (CMC) that found microbial encroachment into the mucus layer — polysorbate 80 has not been tested in an equivalent human trial. In vitro work (e.g. Roberts 2010) shows polysorbate 80 enhances bacterial translocation across intestinal epithelium, and observational data link overall dietary-emulsifier exposure to IBD risk. EFSA is mid re-evaluation of polysorbates (E432–E436). For a supplement excipient with purely cosmetic function (improving the look/texture of soft gels and liquids), the gut-barrier risk profile is unfavorable when safer alternatives (sunflower lecithin, MCT carriers, gum acacia) are widely available.
Magnesium StearateLubricant
A salt of stearic acid used as a lubricant in tablet and capsule production
Polyethylene Glycol (Coating)Coating
A polyether polymer used as a tablet coating and plasticizer
Silicon DioxideAnti-caking
Fine silica powder used to prevent clumping
Microcrystalline CelluloseBinder
Plant-derived cellulose used as a binder and filler in supplements
Croscarmellose SodiumDisintegrant
Cross-linked cellulose derivative used as a superdisintegrant
HypromelloseCapsule
Plant-derived capsule material from cellulose
Stearic AcidLubricant
Saturated fatty acid used as tablet lubricant
How to Take It
Best taken in the evening
Magnesium oxide is poorly absorbed (~4%) and the most laxative form. Most of a dose stays in the gut, which is why it's mainly used for constipation — a poor pick if you're supplementing for magnesium itself.
With or without food
Space it a couple of hours from Iron and Calcium
On the label
Suggested use: Adults, take 1 tablet daily with water and a meal.
General guidance based on the ingredients, not a substitute for the label or your doctor.
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Sources & Scoring
Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).
This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.
The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.