This delivers 1,000 mcg of **methylfolate** (listed as 1,700 mcg DFE), the already-active form of folate your cells use directly without the MTHFR conversion step. That puts it above the 400–800 mcg daily target — a strong dose for supporting red blood cell formation, mood, and healthy cell division, especially for the 40–50% of people who carry a weakened version of the MTHFR enzyme.

Because it skips that conversion entirely, it works regardless of your genetics — which is why it's the folate to reach for if you've been told you carry an MTHFR variant, or during pregnancy when folate demand climbs and neural tube protection matters most.

At this strength it's geared toward correcting a shortfall or higher needs rather than light maintenance. If you're over 60, high folate intake can mask early signs of a B12 deficiency, so keep B12 in range alongside it.

BioStacks
NFH

L-5-MTHF SAP

1 Capsule · 60 servings

iHerbAmazon

Ingredients (1)

L-Methylfolate

100%

Dose

1700 mcg DFE

Target

400–800 mcg

Form

Premium

Other Ingredients

No other ingredients listed

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Sources & Scoring

Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).

This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.

The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.

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