Two capsules of this Sports Research **Berberine** add up to 1,000mg a day — a clinically studied amount for steadying blood sugar, insulin sensitivity, and cholesterol. It works by switching on AMPK, your body's main metabolic regulator, which is why berberine has some of the strongest research of any blood-sugar supplement.

You're getting standard berberine HCl, which the gut absorbs slowly — only a small fraction reaches your blood. That's why clinical studies split the dose across the day: take one capsule with breakfast and one with dinner to keep levels steadier and ease the GI discomfort berberine can cause when taken all at once.

At 1,000mg you're well-dosed, though the trials that matched metformin's effect on glucose used 1,500mg — worth knowing if blood sugar is your main goal. And because berberine interacts with diabetes medications, statins, and blood thinners, clear it with your doctor before combining it with any prescriptions.