This delivers **L-methylfolate** at a therapeutic 5mg — that's 5,000mcg, more than ten times the 400mcg you'd take for everyday folate maintenance. It's the bioactive form of folate your body uses directly, which matters because 40–50% of people carry an MTHFR gene variant that limits how well they convert ordinary folic acid. At this dose, you skip that conversion step entirely.

This isn't an everyday supplement. A 5mg dose sits in practitioner-directed territory — used for diagnosed folate deficiency, strong MTHFR variants, or as a folate adjunct in mood support, where prescription L-methylfolate typically runs 7.5–15mg. If you just want routine coverage, 400–800mcg handles that. The label points you here for a reason: take it under guidance from your healthcare practitioner, as the directions recommend.