Best for
Ingredients (11)
L-Leucine
63%Dose
1250 mg
Target
2000–5000 mg
Form
—
L-Lysine
65%Dose
650 mg
Target
1000–3000 mg
Form
Standard
L-Threonine
70%Dose
350 mg
Target
500–4000 mg
Form
—
L-Isoleucine
42%Dose
625 mg
Target
1500–4000 mg
Form
—
L-Valine
42%Dose
625 mg
Target
1500–4000 mg
Form
—
Other Ingredients (4)
Natural FlavorsFlavor
Broad regulatory category of flavor constituents derived from natural sources. Composition is proprietary and not disclosed — 'Natural Flavors' can include several hundred different compounds depending on the target flavor profile, including hexane-extracted constituents and proprietary carrier solvents. 'Natural' is a regulatory definition (21 CFR §101.22), not a safety guarantee.
Fruit Juice (unspecified)Colorant
Juice or juice concentrate used primarily for natural color and flavor in gummies
Citric AcidAcidulant
Natural acid derived from citrus fruits
Stevia ExtractSweetener
Zero-calorie natural sweetener extracted from the leaves of Stevia rebaudiana
How to Take It
Best taken in the evening
Take at night. Other amino acids compete for brain uptake, so a protein-heavy meal blunts it. Take it between meals, away from food.
On the label
Mix 1 scoop with at least 6 ounces of water one to two times daily or as recommended by your health professional.
Each of these raises serotonin activity on top of St. John's Wort, and together they can trigger serotonin syndrome — agitation, rapid heartbeat, raised blood pressure. Not without medical supervision.
General guidance based on the ingredients, not a substitute for the label or your doctor.
Price Check
$45.00
Pricier than 90% of 11 histidine supplements
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Sources & Scoring
Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).
This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.
The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.