This is a cellular-aging stack built around NAD+ support, and its headline dose holds up. You're getting 415mg of **Nicotinamide Riboside** per 2-capsule serving, comfortably inside the 250–1,000mg range used in human trials. NR reliably raises your blood NAD+ levels — that part has solid evidence — but the downstream anti-aging and metabolic benefits in people are still early-stage, so treat this as support for cellular energy metabolism rather than a proven longevity fix.

Alongside it, **Trans-Resveratrol** at 150mg sits right at the minimum studied dose, and **Quercetin** comes in at 250mg in a phytosome form that absorbs better than standard quercetin — about half the 500mg typically used in trials, though the better-absorbed form narrows that gap for you. Both work through the same SIRT1 cellular-aging pathways as NR, which is why you'll see them stacked together. Just note that resveratrol's natural bioavailability is very low, so its real-world effect is harder to count on.

The betaine is the one number that needs context: at 85mg it's a small fraction of the 2,500mg+ used in performance or homocysteine studies. It's not meant as a standalone betaine dose — it's a methyl-group donor included to replenish the methylation that NR metabolism uses up. If your goal is NAD+ and cellular support, this delivers; if you wanted a therapeutic betaine dose, you'd need far more than what's here.