This is a high-dose, natural full-spectrum vitamin E aimed at antioxidant and liver support, and it pushes well past the everyday range. You're getting 335mg of natural **d-alpha-tocopherol** — about 500 IU — plus 1,000mg of **mixed tocopherols**, for roughly 1,335mg of total vitamin E. The typical supportive range tops out near 268mg (400 IU), so the alpha portion alone clears it; this is a therapeutic-tier dose, not a maintenance one.

The 1,000mg of mixed tocopherols is what makes this full-spectrum rather than alpha-only. That fraction is rich in gamma-tocopherol, which neutralizes a class of reactive molecules that alpha-tocopherol largely misses — giving you broader antioxidant coverage than an alpha-only formula. The natural d- form absorbs roughly twice as efficiently as synthetic vitamin E, and the softgel's MCT oil helps with uptake since the vitamin is fat-soluble. For your liver, higher-dose vitamin E carries real clinical backing, which lines up with this product's intent.

The main thing to weigh is the dose. At about 500 IU of alpha alone, this sits in high-dose territory, where some long-term studies have linked daily intake above 400 IU to a small uptick in health risks, and vitamin E can have a mild blood-thinning effect — worth raising with your doctor if you take anticoagulants. The label's one-to-three-gelcap range lets you start low, and a single gelcap already covers a full day's needs many times over.

BioStacks
Thorne

Ultimate-E

Softgel · 1 Gelcap · 60 servings · $0.83/serving

iHerbAmazon

Best for

Liver

Ingredients (2)

Mixed Tocopherols

100%

Dose

1000 mg

Target

50–268 mg

Form

Premium

Vitamin E

100%

Dose

335 mg

Target

50–268 mg

Form

Premium

Other Ingredients (4)

Medium Chain Triglyceride OilCarrier

Fractionated oils rich in C8/C10 triglycerides used as neutral carrier or anti-sticking agent

GelatinCapsule

Protein derived from collagen, used in traditional capsule shells

GlycerinHumectant

Sweet-tasting liquid used in soft capsules and liquids

Purified WaterSolvent

Water meeting USP specifications used as solvent/vehicle in gummies and liquids

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Sources & Scoring

Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).

This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.

The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.

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