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Best for
Ingredients (1)
Vitamin B12
100%Dose
1200 mcg
Target
250–5000 mcg
Form
Premium
Other Ingredients (4)
CarboxymethylcelluloseThickener
Carboxymethylcellulose was the second emulsifier (with polysorbate 80) in Chassaing et al. 2015 (Nature, PMID 25731162), which showed mucus-barrier thinning, a microbiota shift toward pro-inflammatory species, low-grade inflammation, and metabolic syndrome in mice. Chassaing 2022 (Gastroenterology, PMID 34774538) tested CMC directly in a randomized controlled human feeding trial and found reduced microbial diversity and bacterial encroachment into the normally sterile mucus layer in a susceptible subset of participants. EFSA's 2018 re-evaluation could not establish a safe level due to data gaps. For a purely textural excipient, the gut-barrier risk profile is unfavorable when safer thickeners are widely available.
Magnesium StearateLubricant
A salt of stearic acid used as a lubricant in tablet and capsule production
Calcium CarbonateBuffer
Common calcium salt used as a buffering agent, filler, or mineral fortification in supplements
Microcrystalline CelluloseBinder
Plant-derived cellulose used as a binder and filler in supplements
How to Take It
Best taken in the morning
Many people prefer it earlier in the day; there's no evidence timing changes anything. Absorption is fine with or without food.
With or without food
On the label
1 tablet daily or as directed by a physician. Consult a physician for use beyond 6 months
General guidance based on the ingredients, not a substitute for the label or your doctor.
Price Check
C$16.99≈ $12.40
Cheaper than 70% of 272 vitamin B12 supplements
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Sources & Scoring
Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).
This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.
The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.