BioStacksBest Citrulline for Heart
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Clinical dose: 3000–6000 mg
Citrulline and heart
For heart support, Citrulline is a supporting ingredient backed by research. L-Citrulline is a non-essential amino acid that converts to L-arginine in the kidneys, raising plasma arginine and nitric oxide levels more effectively than oral arginine supplementation (arginine undergoes significant first-pass metabolism). Well-tolerated with no established UL.
Effective dosing
Most evidence supports 3000–6000 mg of citrulline daily. 3-6g/day for NO-mediated blood flow and exercise performance. Citrulline malate studies often use 6-8g (which contains ~3-4.5g pure citrulline). Products below this range may not deliver meaningful results.
What the research says
The clinical evidence for citrulline in heart is moderate. Several trials show it raises nitric oxide more effectively than oral arginine for blood flow Learn more