BioStacks
DaVinci Laboratories

5-HTP 50 mg

1 Capsule × 3/day · 90 servings · $0.39/serving

iHerbAmazon

Best for

Sleep

Ingredients (2)

Vitamin B6

100%

Dose/day

15 mg

Target

1.3–25 mg

Form

—

5-HTP

100%

Dose/day

150 mg

Target

100–300 mg

Form

—

Other Ingredients (3)

Silicon DioxideAnti-caking

Fine silica powder used to prevent clumping

HypromelloseCapsule

Plant-derived capsule material from cellulose

Microcrystalline CelluloseBinder

Plant-derived cellulose used as a binder and filler in supplements

How to Take It

Best taken in the evening

Contains 5-HTP, so it belongs in the evening. Vitamin B6 is easier on the stomach taken with food.

With food

5-HTP does better on an empty stomach, but something else in this bottle needs food. Taking the whole product with a meal is the better trade — an upset stomach is why most people stop.

Keep it away from protein-heavy meals
Space it a couple of hours from SAMe
Label directs 3 servings — keep one for the evening

On the label

As a dietary supplement, take 1 capsule 20 minutes before a meal, three times daily, or as directed by your healthcare practitioner.

Do not combine with St. John's Wort

Each of these raises serotonin activity on top of St. John's Wort, and together they can trigger serotonin syndrome — agitation, rapid heartbeat, raised blood pressure. Not without medical supervision.

General guidance based on the ingredients, not a substitute for the label or your doctor.

Price Check

$34.82

$10$20$50

Pricier than 77% of 187 vitamin B6 supplements

Track this supplement in your stack

Get personalized insights, interactions, and coverage recommendations.

Get Started Free

Similar Supplements

5-HTP Synergy™

Designs for Health

5-HTP Synergy™

😴 for Sleep

78
5-HTP Supreme™

Designs for Health

5-HTP Supreme™

🧘 for Stress & Mood

72
5-HTP

Thorne

5-HTP

😴 for Sleep

70
5-HTP 200 mg

NutraBio

5-HTP 200 mg

🧘 for Stress & Mood

69
5-HTP Plus+ 200 mg

NatureWise

5-HTP Plus+ 200 mg

😴 for Sleep

55

Sources & Scoring

Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).

This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.

The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.

BioStacks

Know exactly what's in your supplements.

Navigate

  • Home
  • App Store
  • Google Play

Resources

  • Contact & Support
  • Pricing
  • Terms of Service
  • Privacy Policy
  • Refund Policy

Explore

  • Health Areas
  • Best Supplements
  • Nutrients
  • All Supplements

Popular Picks

  • Best Magnesium for Sleep
  • Best Collagen for Skin
  • Best Creatine for Muscle
  • Best Vitamin D for Bone Health
  • Best Probiotics for Digestion
  • Best CoQ10 for Heart
© 2026 BioStacks. All rights reserved. Not medical advice.