Best for
Ingredients (2)
Vitamin B6
100%Dose
5 mg
Target
1.3–25 mg
Form
Premium
5-HTP
100%Dose
200 mg
Target
100–300 mg
Form
—
Other Ingredients (4)
Rice ExtractFiller
Rice-based ingredients carry risk of inorganic arsenic contamination. Vague labeling — 'rice extract' does not specify what is extracted or standardized. Used as a cheap filler with no supplemental benefit.
Rice FlourFiller
Rice-based ingredients carry risk of inorganic arsenic contamination (FDA and Consumer Reports). Rice accumulates arsenic from soil at higher rates than other grains. Used as a cheap filler — adds nothing beneficial.
Gellan GumGelling Agent
Microbial polysaccharide produced by Sphingomonas elodea, used as a gelling and stabilizing agent
HypromelloseCapsule
Plant-derived capsule material from cellulose
How to Take It
Best taken in the evening
Contains 5-HTP, so it belongs in the evening. Vitamin B6 is easier on the stomach taken with food.
5-HTP does better on an empty stomach, but something else in this bottle needs food. Taking the whole product with a meal is the better trade — an upset stomach is why most people stop.
On the label
Adults take 1 capsule daily with food or as recommended by your healthcare provider.
Each of these raises serotonin activity on top of St. John's Wort, and together they can trigger serotonin syndrome — agitation, rapid heartbeat, raised blood pressure. Not without medical supervision.
General guidance based on the ingredients, not a substitute for the label or your doctor.
Price Check
$19.99
Near the median of 187 vitamin B6 supplements
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Sources & Scoring
Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).
This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.
The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.