BioStacks
Best for
Ingredients (6)
Vitamin B6
100%Dose
10 mg
Target
1.3–25 mg
Form
—
Niacin
100%Dose
30 mg ne
Target
25–500 mg
Form
—
Biotin
5%Dose
50 mcg
Target
1000–5000 mcg
Form
—
5-HTP
100%Dose
100 mg
Target
100–300 mg
Form
—
Zinc
33%Dose
5 mg
Target
15–30 mg
Form
Not listed
Other Ingredients (10)
Rice FlourFiller
Rice-based ingredients carry risk of inorganic arsenic contamination (FDA and Consumer Reports). Rice accumulates arsenic from soil at higher rates than other grains. Used as a cheap filler — adds nothing beneficial.
BiotinFood
Vitamin B7, a water-soluble B-vitamin.
Folic AcidVitamin
Synthetic form of vitamin B9 used for fortification — supports red blood cell formation and neural tube development. Pharmacologically distinct from the natural/active form (5-methyltetrahydrofolate, methylfolate).
Magnesium StearateLubricant
A salt of stearic acid used as a lubricant in tablet and capsule production
Silicon DioxideAnti-caking
Fine silica powder used to prevent clumping
Capsule ShellCapsule
Generic capsule shell where the label does not specify the material. Common materials are hypromellose (HPMC) for vegetarian capsules and gelatin for traditional capsules — both are GRAS-listed and safe. Fish gelatin and pullulan variants also exist.
NicotinamideVitamin
Amide form of vitamin B3 used for fortification; supports cellular energy and NAD+ synthesis without flushing
L-5-Hydroxytryptophan
Not reviewed yet
How to Take It
Best taken in the evening
Contains 5-HTP, so it belongs in the evening. Take it with food — the zinc and niacin in it are what makes this kind of product feel nauseating on an empty stomach.
With food
5-HTP does better on an empty stomach, but something else in this bottle needs food. Taking the whole product with a meal is the better trade — an upset stomach is why most people stop.
Keep it away from protein-heavy meals
Space it a couple of hours from Iron, Calcium and SAMe
On the label
Take 1 capsule a day preferably before bed with a carbohydrate snack. Do not exceed recommended daily intake. Food supplements should not be used as a substitute for a varied and balanced diet and healthy lifestyle.
Do not combine with St. John's Wort
Each of these raises serotonin activity on top of St. John's Wort, and together they can trigger serotonin syndrome — agitation, rapid heartbeat, raised blood pressure. Not without medical supervision.
General guidance based on the ingredients, not a substitute for the label or your doctor.
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Sources & Scoring
Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).
This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.
The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.