BioStacks
Pure Encapsulations

SeroPlus

2 Capsules · 60 servings

iHerbAmazon
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What it does

A combination of 9 label ingredients.

Vitamin B6

pyridoxal 5-phosphatePremium

Supports normal protein metabolism, neurotransmitter production and hemoglobin formation.

Vitamin B3

niacinamideStandard

Helps convert food into cellular energy and supports normal metabolic reactions.

General HealthEnergy
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Ingredients (10)

Other ingredients

Capsule ShellCapsule

Generic capsule shell where the label does not specify the material. Common materials are hypromellose (HPMC) for vegetarian capsules and gelatin for traditional capsules — both are GRAS-listed and safe. Fish gelatin and pullulan variants also exist.

Lab testing

How to take it

With food

5-HTP does better on an empty stomach, but something else in this bottle needs food. Taking the whole product with a meal is the better trade — an upset stomach is why most people stop.

Keep it away from protein-heavy meals
Space it a couple of hours from Iron, Calcium and SAMe

On the label

As a dietary supplement, take 1 capsule daily, with a meal, or as directed by a health professional.

Do not combine with St. John's Wort

Each of these raises serotonin activity on top of St. John's Wort, and together they can trigger serotonin syndrome — agitation, rapid heartbeat, raised blood pressure. Not without medical supervision.

Price check

$55.20

$0.92 / serving

$10$20$50

Pricier than 90% of 40 general health supplements

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Sources & Scoring

Nutrient data (RDA, UL, and safety thresholds) sourced from the NIH Office of Dietary Supplements and the National Academies Dietary Reference Intakes (DRI).

This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.

The score analyzes what's on the label: ingredient doses vs. studied ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.

Not medical advice. Consult your healthcare professional.

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