BioStacks
Best for
Ingredients (10)
Folate
100%Dose
833 mcg DFE
Target
400–800 mcg
Form
Premium
L-5-MTHF
100%Dose
500 mcg
Target
400–800 mcg
Form
Premium
Vitamin B6
100%Dose
6.7 mg
Target
1.3–25 mg
Form
Premium
Magnesium
100%Dose
100 mg
Target
100–400 mg
Form
Standard
Zinc
67%Dose
10 mg
Target
15–30 mg
Form
Premium
Other Ingredients (1)
Capsule ShellCapsule
Generic capsule shell where the label does not specify the material. Common materials are hypromellose (HPMC) for vegetarian capsules and gelatin for traditional capsules — both are GRAS-listed and safe. Fish gelatin and pullulan variants also exist.
How to Take It
Best taken in the evening
Contains 5-HTP, so it belongs in the evening. Take it with food — the zinc in it is what makes this kind of product feel nauseating on an empty stomach.
With food
5-HTP does better on an empty stomach, but something else in this bottle needs food. Taking the whole product with a meal is the better trade — an upset stomach is why most people stop.
Keep it away from protein-heavy meals
Space it a couple of hours from Iron, Calcium and SAMe
On the label
As a dietary supplement, take 1 capsule daily, with a meal, or as directed by a health professional.
Do not combine with St. John's Wort
Each of these raises serotonin activity on top of St. John's Wort, and together they can trigger serotonin syndrome — agitation, rapid heartbeat, raised blood pressure. Not without medical supervision.
General guidance based on the ingredients, not a substitute for the label or your doctor.
Price Check
$55.20
Pricier than 90% of 40 general health supplements
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Sources & Scoring
Nutrient data (RDA, UL, and safety thresholds) sourced from the NIH Office of Dietary Supplements and the National Academies Dietary Reference Intakes (DRI).
This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.
The score analyzes what's on the label: ingredient doses vs. studied ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.