BioStacks
HoltraCeuticals

B12 Methyl Factors

1 Tablet · 60 servings · $0.48/serving

iHerbAmazon

Best for

Energy

Ingredients (3)

Vitamin B12

100%

Dose

5000 mcg

Target

250–5000 mcg

Form

Premium

Quatrefolic

100%

Dose

1000 mcg

Target

400–800 mcg

Form

Premium

Folate

100%

Dose

1700 mcg DFE

Target

400–800 mcg

Form

Not listed

Other Ingredients (10)

IsomaltSweetener

A poorly-absorbed sugar alcohol that can cause bloating, gas, and laxative effects at higher doses (EFSA notes laxative threshold for polyols). Tolerable for most, but cumulative across products.

SucroseSweetener

Added sugars and high glycemic load; dental caries risk

Fruit Juice (unspecified)Colorant

Juice or juice concentrate used primarily for natural color and flavor in gummies

Natural Cherry FlavorFlavor

A flavoring derived from natural cherry sources

Silicon DioxideAnti-caking

Fine silica powder used to prevent clumping

Citric AcidAcidulant

Natural acid derived from citrus fruits

Croscarmellose SodiumDisintegrant

Cross-linked cellulose derivative used as a superdisintegrant

PotassiumMineral

Essential mineral naturally present in many plant-based supplement ingredients

How to Take It

Best taken in the morning

Many people prefer it earlier in the day; there's no evidence timing changes anything. Absorption is fine with or without food.

With or without food

On the label

1 tablet per day or as recommended by your health care professional.

General guidance based on the ingredients, not a substitute for the label or your doctor.

Price Check

$29.00

$10$20$50

Pricier than 85% of 250 vitamin B12 supplements

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Sources & Scoring

Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).

This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.

The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.

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