This two-ingredient capsule delivers folate and B12 in their already-active forms at doses that hit clinical ranges for energy, methylation, and healthy red blood cell production. You're getting **folate** as L-methylfolate at 680 mcg DFE — about 400 mcg of actual methylfolate, since methylfolate counts as roughly 1.7x its weight in DFE — in the form your body can use directly, with none of the conversion step that synthetic folic acid requires. That matters for the 40–50% of people carrying MTHFR gene variants, who convert standard folic acid poorly: here you skip that bottleneck entirely and get folate your cells can actually put to work.
**Vitamin B12** comes as methylcobalamin at 300 mcg, again an active form you use straight away, sitting comfortably within the 250–5,000 mcg range supplements use to overcome low absorption. Pairing the two is the responsible design rather than a marketing flourish: folate and B12 work side by side in methylation and red blood cell formation, and taking high-dose folate on its own can mask a developing B12 deficiency. Delivering both together closes that gap.
This is a strong fit if you're vegan, over 50, planning a pregnancy, or know you carry an MTHFR variant — all groups where one or both of these nutrients run low or convert poorly. At one capsule daily with both in ready-to-use form, you reach an effective intake without guesswork.
Best for
Ingredients (2)
Folate
100%Dose
680 mcg DFE
Target
400–800 mcg
Form
Premium
Vitamin B12
100%Dose
300 mcg
Target
250–5000 mcg
Form
Premium
Other Ingredients (3)
Dicalcium PhosphateBinder
Calcium and phosphorus compound used as binder
Microcrystalline CelluloseBinder
Plant-derived cellulose used as a binder and filler in supplements
Microcrystalline CelluloseBinder
Plant-derived cellulose used as a binder and filler in supplements
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Sources & Scoring
Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).
This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.
The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.