BioStacks
Best for
Ingredients (20)
Vitamin A
100%Dose
1050 mcg RAE
Target
700–1500 mcg
Form
Standard
Vitamin D3
80%Dose
800 IU
Target
1000–5000 IU
Form
Premium
Pantothenic Acid
14%Dose
6.8 mg
Target
50–500 mg
Form
Premium
Vitamin B12
3%Dose
6.8 mcg
Target
250–5000 mcg
Form
Premium
Folate
86%Dose
345 mcg DFE
Target
400–800 mcg
Form
Premium
Other Ingredients (13)
ErythritolSweetener
Witkowski et al. 2023 (Nature Medicine, PMID 36849732) reported elevated plasma erythritol associated with major adverse cardiovascular events (MACE) in two cohorts (n=4,000+), with in-vitro and ex-vivo evidence of enhanced platelet aggregation. Replication is ongoing; FDA and EFSA have not changed their safety positions, but the signal is real and the additive is purely cosmetic. Better-established concern: GI tolerance — single doses above ~50 g cause osmotic diarrhea. Lower threshold for children.
IsomaltSweetener
A poorly-absorbed sugar alcohol that can cause bloating, gas, and laxative effects at higher doses (EFSA notes laxative threshold for polyols). Tolerable for most, but cumulative across products.
XylitolSweetener
A FODMAP sugar alcohol that can cause GI distress (bloating, gas, diarrhea) at moderate doses (>10-20g/day), though supplement amounts are typically small. Extremely toxic to dogs — households with pets should store securely.
AnnattoColorant
Natural yellow-orange colorant derived from the seeds of the achiote tree (Bixa orellana)
Natural FlavorsFlavor
Broad regulatory category of flavor constituents derived from natural sources. Composition is proprietary and not disclosed — 'Natural Flavors' can include several hundred different compounds depending on the target flavor profile, including hexane-extracted constituents and proprietary carrier solvents. 'Natural' is a regulatory definition (21 CFR §101.22), not a safety guarantee.
Tapioca FiberFiber
Soluble fiber derived from tapioca, used as a bulking agent and prebiotic fiber filler
Sunflower Seed OilCarrier
Common vegetable oil from sunflower seeds used as a carrier in softgels for fat-soluble nutrients
Black CarrotColorant
Natural colorant derived from anthocyanin-rich black carrots, used to provide purple/red color in gummies and chewables
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Sources & Scoring
Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).
This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.
The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.