BioStacks
Natural Factors

Vitamin C, Time Release, 1,000 mg

1 Tablet · 90 servings · $0.11/serving

iHerbAmazon

Best for

Immune

Ingredients (3)

Vitamin C

100%

Dose

1000 mg

Target

250–2000 mg

Form

Budget

Citrus Bioflavonoids Extract 4:1from 200 mg of citrus fruits

20%

Dose

50 mg

Target

250–1000 mg

Form

—

Hesperidin Extract 4:1from 100 mg of orange

5%

Dose

25 mg

Target

500–1000 mg

Form

—

Other Ingredients (8)

CarboxymethylcelluloseThickener

Carboxymethylcellulose was the second emulsifier (with polysorbate 80) in Chassaing et al. 2015 (Nature, PMID 25731162), which showed mucus-barrier thinning, a microbiota shift toward pro-inflammatory species, low-grade inflammation, and metabolic syndrome in mice. Chassaing 2022 (Gastroenterology, PMID 34774538) tested CMC directly in a randomized controlled human feeding trial and found reduced microbial diversity and bacterial encroachment into the normally sterile mucus layer in a susceptible subset of participants. EFSA's 2018 re-evaluation could not establish a safe level due to data gaps. For a purely textural excipient, the gut-barrier risk profile is unfavorable when safer thickeners are widely available.

Coating (unspecified)Coating

Generic tablet coating declaration where the label does not itemize the coating's components; modern aqueous film coatings are typically cellulose-based (HPMC) with a plasticizer

Magnesium StearateLubricant

A salt of stearic acid used as a lubricant in tablet and capsule production

Silicon DioxideAnti-caking

Fine silica powder used to prevent clumping

Dicalcium PhosphateBinder

Calcium and phosphorus compound used as binder

Hydroxypropyl CelluloseBinder

An inert modified-cellulose polymer used as a binder, film-former, and disintegrant.

Microcrystalline CelluloseBinder

Plant-derived cellulose used as a binder and filler in supplements

Stearic AcidLubricant

Saturated fatty acid used as tablet lubricant

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Sources & Scoring

Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).

This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.

The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.

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