BioStacks
Nature Made

Iron 65 mg

1 Tablet · 365 servings

iHerbAmazon

Best for

Energy

Ingredients (2)

Iron

100%

Dose

65 mg

Target

15–45 mg

Form

Budget

Calcium

18 mg

Trace amount — not scored

Other Ingredients (7)

Polysorbate 80Emulsifier

Chassaing et al. 2015 (Nature, PMID 25731162) tested polysorbate 80 directly and showed it thinned the gut mucus barrier, altered microbiota composition, and induced low-grade inflammation and metabolic syndrome in mice. The strongest human evidence is for a related emulsifier rather than polysorbate 80 itself: Chassaing 2022 (Gastroenterology, PMID 34774538) was a controlled human feeding RCT of carboxymethylcellulose (CMC) that found microbial encroachment into the mucus layer — polysorbate 80 has not been tested in an equivalent human trial. In vitro work (e.g. Roberts 2010) shows polysorbate 80 enhances bacterial translocation across intestinal epithelium, and observational data link overall dietary-emulsifier exposure to IBD risk. EFSA is mid re-evaluation of polysorbates (E432–E436). For a supplement excipient with purely cosmetic function (improving the look/texture of soft gels and liquids), the gut-barrier risk profile is unfavorable when safer alternatives (sunflower lecithin, MCT carriers, gum acacia) are widely available.

Magnesium StearateLubricant

A salt of stearic acid used as a lubricant in tablet and capsule production

Polyethylene Glycol (Coating)Coating

A polyether polymer used as a tablet coating and plasticizer

Microcrystalline CelluloseBinder

Plant-derived cellulose used as a binder and filler in supplements

Croscarmellose SodiumDisintegrant

Cross-linked cellulose derivative used as a superdisintegrant

HypromelloseCapsule

Plant-derived capsule material from cellulose

Triethyl CitrateCoating

A citric acid ester used as a plasticizer in film and enteric coatings

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Sources & Scoring

Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).

This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.

The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.

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