Best for
Ingredients (2)
Iron
100%Dose
65 mg
Target
15–45 mg
Form
Budget
Calcium
18 mgTrace amount — not scored
Other Ingredients (7)
Polysorbate 80Emulsifier
Chassaing et al. 2015 (Nature, PMID 25731162) tested polysorbate 80 directly and showed it thinned the gut mucus barrier, altered microbiota composition, and induced low-grade inflammation and metabolic syndrome in mice. The strongest human evidence is for a related emulsifier rather than polysorbate 80 itself: Chassaing 2022 (Gastroenterology, PMID 34774538) was a controlled human feeding RCT of carboxymethylcellulose (CMC) that found microbial encroachment into the mucus layer — polysorbate 80 has not been tested in an equivalent human trial. In vitro work (e.g. Roberts 2010) shows polysorbate 80 enhances bacterial translocation across intestinal epithelium, and observational data link overall dietary-emulsifier exposure to IBD risk. EFSA is mid re-evaluation of polysorbates (E432–E436). For a supplement excipient with purely cosmetic function (improving the look/texture of soft gels and liquids), the gut-barrier risk profile is unfavorable when safer alternatives (sunflower lecithin, MCT carriers, gum acacia) are widely available.
Magnesium StearateLubricant
A salt of stearic acid used as a lubricant in tablet and capsule production
Polyethylene Glycol (Coating)Coating
A polyether polymer used as a tablet coating and plasticizer
Microcrystalline CelluloseBinder
Plant-derived cellulose used as a binder and filler in supplements
Croscarmellose SodiumDisintegrant
Cross-linked cellulose derivative used as a superdisintegrant
HypromelloseCapsule
Plant-derived capsule material from cellulose
Triethyl CitrateCoating
A citric acid ester used as a plasticizer in film and enteric coatings
How to Take It
Best taken in the morning
Ferrous sulfate is the form most likely to upset your stomach. Food costs you some absorption but is usually the difference between sticking with it and quitting.
On the label
Suggested use: Adults, for iron deficiency, take one tablet daily. For easier swallowing, take with water before and during ingestion. Taking with a meal may minimize the possibility of stomach upset.
General guidance based on the ingredients, not a substitute for the label or your doctor.
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Sources & Scoring
Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).
This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.
The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.