BioStacks
Nutricost

L-Tryptophan 500 mg

1 Capsule · 120 servings · $0.12/serving

iHerbAmazon

Best for

Sleep

Ingredients (2)

BioPerine Black Pepper extract

100%

Dose

5 mg

Target

5–20 mg

Form

—

L-Tryptophan

100%

Dose

500 mg

Target

250–1000 mg

Form

—

Other Ingredients (4)

Rice FlourFiller

Rice-based ingredients carry risk of inorganic arsenic contamination (FDA and Consumer Reports). Rice accumulates arsenic from soil at higher rates than other grains. Used as a cheap filler — adds nothing beneficial.

Magnesium StearateLubricant

A salt of stearic acid used as a lubricant in tablet and capsule production

Silicon DioxideAnti-caking

Fine silica powder used to prevent clumping

Capsule ShellCapsule

Generic capsule shell where the label does not specify the material. Common materials are hypromellose (HPMC) for vegetarian capsules and gelatin for traditional capsules — both are GRAS-listed and safe. Fish gelatin and pullulan variants also exist.

How to Take It

Best taken in the evening

Contains Tryptophan, so it belongs in the evening. Black Pepper Extract is easier on the stomach taken with food.

With food

Tryptophan does better on an empty stomach, but something else in this bottle needs food. Taking the whole product with a meal is the better trade — an upset stomach is why most people stop.

Keep it away from protein-heavy meals
Space it a couple of hours from SAMe

On the label

As a dietary supplement, take 1-2 capsules 2-3 times daily, preferably on an empty stomach

Do not combine with St. John's Wort

Each of these raises serotonin activity on top of St. John's Wort, and together they can trigger serotonin syndrome — agitation, rapid heartbeat, raised blood pressure. Not without medical supervision.

General guidance based on the ingredients, not a substitute for the label or your doctor.

Price Check

$14.95

$10$20$50

Cheaper than 71% of 18 tryptophan supplements

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Sources & Scoring

Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).

This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.

The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.

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