Best for
Ingredients (5)
Vitamin B12
100%Dose
1000 mcg
Target
250–5000 mcg
Form
Premium
Vitamin B6
100%Dose
50 mg
Target
25–100 mg
Form
Premium
Folic Acid
100%Dose
5000 mcg
Target
400–800 mcg
Form
Budget
Folate
100%Dose
8500 mcg DFE
Target
400–800 mcg
Form
Not listed
Betaine
20%Dose
500 mg
Target
2500–6000 mg
Form
—
Other Ingredients (4)
Magnesium StearateLubricant
A salt of stearic acid used as a lubricant in tablet and capsule production
Calcium SilicateAnti-caking
Inorganic compound used as an anti-caking and flow agent in powdered supplements
Stearic AcidLubricant
Saturated fatty acid used as tablet lubricant
HypromelloseCapsule
Plant-derived capsule material from cellulose
How to Take It
Best taken in the morning
The Vitamin B12 in it is what pulls this toward the morning. Vitamin B6 is easier on the stomach taken with food.
On the label
1 or more capsules per day or as recommended by your health care professional.
General guidance based on the ingredients, not a substitute for the label or your doctor.
Price Check
$57.10
Pricier than 81% of 34 TMG (Trimethylglycine) supplements
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Sources & Scoring
Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).
This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.
The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.