Every active here is dosed below the amount studied to work. See how each one compares in the breakdown below.
Best for
Ingredients (1)
SAMe
25%Dose
200 mg
Target
800–1600 mg
Form
Premium
Other Ingredients (5)
Ascorbyl PalmitateAntioxidant
Fat-soluble form of vitamin C used as preservative
Calcium CarbonateBuffer
Common calcium salt used as a buffering agent, filler, or mineral fortification in supplements
Calcium CarbonateBuffer
Common calcium salt used as a buffering agent, filler, or mineral fortification in supplements
Hypoallergenic Plant FiberFiller
Plant-derived cellulose fiber used as a hypoallergenic filler, common in Thorne and Pure Encapsulations products
Capsule ShellCapsule
Generic capsule shell where the label does not specify the material. Common materials are hypromellose (HPMC) for vegetarian capsules and gelatin for traditional capsules — both are GRAS-listed and safe. Fish gelatin and pullulan variants also exist.
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Sources & Scoring
Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).
This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.
The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.