BioStacks
Webber Naturals
Sleep Cycle Melatonin with L-Theanine, 5-HTP & Sleep Botanicals
1 Tablet · 60 servings
Best for
Ingredients (6)
Melatonin
100%Dose
10 mg
Target
0.5–5 mg
Form
—
L-Theanine
100%Dose
200 mg
Target
100–250 mg
Form
—
L-5-Hydroxytryptophan
15%Dose
15 mg
Target
100–300 mg
Form
—
Hops Extract 5:1
10%Dose
10 mg
Target
100–500 mg
Form
—
Passionflower Extract 4:1
8%Dose
20 mg
Target
250–500 mg
Form
—
Other Ingredients (10)
CarboxymethylcelluloseThickener
Carboxymethylcellulose was the second emulsifier (with polysorbate 80) in Chassaing et al. 2015 (Nature, PMID 25731162), which showed mucus-barrier thinning, a microbiota shift toward pro-inflammatory species, low-grade inflammation, and metabolic syndrome in mice. Chassaing 2022 (Gastroenterology, PMID 34774538) tested CMC directly in a randomized controlled human feeding trial and found reduced microbial diversity and bacterial encroachment into the normally sterile mucus layer in a susceptible subset of participants. EFSA's 2018 re-evaluation could not establish a safe level due to data gaps. For a purely textural excipient, the gut-barrier risk profile is unfavorable when safer thickeners are widely available.
Coating (unspecified)Coating
Generic tablet coating declaration where the label does not itemize the coating's components; modern aqueous film coatings are typically cellulose-based (HPMC) with a plasticizer
Silicon DioxideAnti-caking
Fine silica powder used to prevent clumping
Magnesium StearateLubricant
A salt of stearic acid used as a lubricant in tablet and capsule production
Croscarmellose SodiumDisintegrant
Cross-linked cellulose derivative used as a superdisintegrant
Dicalcium PhosphateBinder
Calcium and phosphorus compound used as binder
Hydroxypropyl CelluloseBinder
An inert modified-cellulose polymer used as a binder, film-former, and disintegrant.
Microcrystalline CelluloseBinder
Plant-derived cellulose used as a binder and filler in supplements
How to Take It
Best taken in the evening
Take 30–60 minutes before bed. It's a circadian signal, not a daytime supplement. Take it between meals, away from food.
On an empty stomach
Keep it away from protein-heavy meals
Space it a couple of hours from SAMe
On the label
At or before bedtime, 1 tablet daily or as directed by a physician
Do not combine with St. John's Wort
Each of these raises serotonin activity on top of St. John's Wort, and together they can trigger serotonin syndrome — agitation, rapid heartbeat, raised blood pressure. Not without medical supervision.
General guidance based on the ingredients, not a substitute for the label or your doctor.
Price Check
C$23.29≈ $17.00
Pricier than 79% of 187 melatonin supplements
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Sources & Scoring
Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).
This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.
The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.