BioStacksALA and liver
When it comes to liver, ALA is one of the most supporting nutrients to consider. Alpha-lipoic acid is a sulfur-containing compound that functions as a cofactor for mitochondrial enzymes and is both water- and fat-soluble, giving it unique antioxidant versatility. It regenerates other antioxidants (vitamins C, E, glutathione, CoQ10). R-lipoic acid is the biologically active enantiomer with ~2x the bioavailability of racemic ALA; most supplements contain the racemic (R/S) mixture, where the 50% inactive S-form competes with R-ALA for absorption.
How much ala do you need
Research points to 300–600 mg as the effective range for ala. Most studies use 300–600 mg/day of racemic ALA. R-lipoic acid (the natural form) is more bioavailable and used at lower doses (100–300 mg). Doses up to 1200 mg/day used in diabetic neuropathy research. Lower doses may provide some benefit, but most studies showing clear results used this range.
What the research says
The clinical evidence for ala in liver is strong. Strong clinical data for diabetic neuropathy and glucose metabolism across multiple trials Learn more