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Life Extension

Bone Restore Chewable Tablet Chocolate Flavored

2 Tablets · 30 servings

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What it does

A combination of 9 label ingredients.

Vitamin D

Mixed formsGrade —

Supports calcium absorption and the maintenance of normal bones.

Calcium

Mixed formsGrade —

Supports the maintenance of normal bones and teeth, muscle function and nerve signaling.

DentalBone & JointImmune
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Ingredients (8)

IngredientDoseTarget/referenceForm

Nutrition

Calories, macros & sodium.

  • Sodium10 mg

Other ingredients

CarboxymethylcelluloseThickener

Carboxymethylcellulose was the second emulsifier (with polysorbate 80) in Chassaing et al. 2015 (Nature, PMID 25731162), which showed mucus-barrier thinning, a microbiota shift toward pro-inflammatory species, low-grade inflammation, and metabolic syndrome in mice. Chassaing 2022 (Gastroenterology, PMID 34774538) tested CMC directly in a randomized controlled human feeding trial and found reduced microbial diversity and bacterial encroachment into the normally sterile mucus layer in a susceptible subset of participants. EFSA's 2018 re-evaluation could not establish a safe level due to data gaps. For a purely textural excipient, the gut-barrier risk profile is unfavorable when safer thickeners are widely available.

MaltodextrinBinder

Spikes blood sugar faster than table sugar (glycemic index 85–105). Research links it to gut bacteria changes that may promote intestinal inflammation (Nickerson et al. 2015). Used as a cheap filler — adds nothing beneficial.

Rice FlourFiller

Rice-based ingredients carry risk of inorganic arsenic contamination (FDA and Consumer Reports). Rice accumulates arsenic from soil at higher rates than other grains. Used as a cheap filler — adds nothing beneficial.

XylitolSweetener

A FODMAP sugar alcohol that can cause GI distress (bloating, gas, diarrhea) at moderate doses (>10-20g/day), though supplement amounts are typically small. Extremely toxic to dogs — households with pets should store securely.

Natural FlavorsFlavor

Broad regulatory category of flavor constituents derived from natural sources. Composition is proprietary and not disclosed — 'Natural Flavors' can include several hundred different compounds depending on the target flavor profile, including hexane-extracted constituents and proprietary carrier solvents. 'Natural' is a regulatory definition (21 CFR §101.22), not a safety guarantee.

Silicon DioxideAnti-caking

Fine silica powder used to prevent clumping

Vegetable StearateLubricant

A plant-derived salt of stearic acid (typically magnesium or calcium) used as a tablet lubricant

CocoaFlavor

Common food ingredient used for chocolate flavoring in supplements

Lab testing

How to take it

With a meal containing fat
Keep it away from high-oxalate foods like spinach
Space it a couple of hours from Iron

On the label

Chew two (2) tablets daily, or as recommended by a healthcare practitioner. Scientific studies suggest calcium supplementation in divided doses with food in the morning and evening may yield best results. Do not swallow tablets whole. Maintaining an optimal vitamin D blood level also helps maximize calcium absorption.

Price check

$16.50

$0.55 / serving

$10$20$50

Cheaper than 74% of 95 dental supplements

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Sources & Scoring

Nutrient data (RDA, UL, and safety thresholds) sourced from the NIH Office of Dietary Supplements and the National Academies Dietary Reference Intakes (DRI).

This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.

The score analyzes what's on the label: ingredient doses vs. studied ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.

Not medical advice. Consult your healthcare professional.

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