BioStacks
Natrol

Mood Positive 5-HTP

1 Tablet · 50 servings · $0.14/serving

39 / 100Poor

Score Breakdown

Formulation
50
Safety
75
Final score
39/100

Ingredients (7)

Vitamin B6

100%

Dose

10 mg

Target

1.3–25 mg

Form

Premium

Vitamin B12

20%

Dose

50 mcg

Target

250–5000 mcg

Form

Budget

Folate

85%

Dose

340 mcg dfe

Target

400–800 mcg

Form

Not listed

Suntheanine L-Theanine

50%

Dose

50 mg

Target

100–250 mg

Form

Premium

Folic Acid

50%

Dose

200 mcg

Target

400–800 mcg

Form

Budget

Other Ingredients (9)

CarboxymethylcelluloseThickener

Carboxymethylcellulose was the second emulsifier (with polysorbate 80) in Chassaing et al. 2015 (Nature, PMID 25731162), which showed mucus-barrier thinning, a microbiota shift toward pro-inflammatory species, low-grade inflammation, and metabolic syndrome in mice. Chassaing 2022 (Gastroenterology, PMID 34774538) tested CMC directly in a randomized controlled human feeding trial and found reduced microbial diversity and bacterial encroachment into the normally sterile mucus layer in a susceptible subset of participants. EFSA's 2018 re-evaluation could not establish a safe level due to data gaps. For a purely textural excipient, the gut-barrier risk profile is unfavorable when safer thickeners are widely available.

Magnesium StearateLubricant

A salt of stearic acid used as a lubricant in tablet and capsule production

Silicon DioxideAnti-caking

Fine silica powder used to prevent clumping

Calcium CarbonateBuffer

Common calcium salt used as a buffering agent, filler, or mineral fortification in supplements

GlycerinHumectant

Sweet-tasting liquid used in soft capsules and liquids

HypromelloseCapsule

Plant-derived capsule material from cellulose

Microcrystalline CelluloseBinder

Plant-derived cellulose used as a binder and filler in supplements

Microcrystalline CelluloseBinder

Plant-derived cellulose used as a binder and filler in supplements

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Sources & Scoring

Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).

This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.

The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.