BioStacks
Metagenics

SeroSyn™

1 Capsule × 3/day · 90 servings · $0.99/serving

iHerbAmazon

Best for

Stress & MoodSleepEnergy

Ingredients (7)

Folate

100%

Dose/day

1665 mcg DFE

Target

400–800 mcg

Form

Premium

Vitamin B12

100%

Dose/day

750 mcg

Target

250–5000 mcg

Form

Premium

Vitamin B6

100%

Dose/day

30 mg

Target

1.3–25 mg

Form

Premium

L-Theanine

100%

Dose/day

240 mg

Target

100–250 mg

Form

—

Asian Ginseng (Panax ginseng) root extract

100%

Dose/day

300 mg

Target

200–400 mg

Form

—

Other Ingredients (4)

Silicon DioxideAnti-caking

Fine silica powder used to prevent clumping

Stearic AcidLubricant

Saturated fatty acid used as tablet lubricant

Microcrystalline CelluloseBinder

Plant-derived cellulose used as a binder and filler in supplements

Capsule ShellCapsule

Generic capsule shell where the label does not specify the material. Common materials are hypromellose (HPMC) for vegetarian capsules and gelatin for traditional capsules — both are GRAS-listed and safe. Fish gelatin and pullulan variants also exist.

How to Take It

Best taken in the evening

Contains 5-HTP, so it belongs in the evening. Vitamin B6 is easier on the stomach taken with food.

With food

5-HTP does better on an empty stomach, but something else in this bottle needs food. Taking the whole product with a meal is the better trade — an upset stomach is why most people stop.

Keep it away from protein-heavy meals
Space it a couple of hours from SAMe
Label directs 3 servings — keep one for the evening

On the label

Take one capsule three times daily with food or as directed by your healthcare practitioner.

Do not combine with St. John's Wort

Each of these raises serotonin activity on top of St. John's Wort, and together they can trigger serotonin syndrome — agitation, rapid heartbeat, raised blood pressure. Not without medical supervision.

General guidance based on the ingredients, not a substitute for the label or your doctor.

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Sources & Scoring

Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).

This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.

The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.

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