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Renue By Science

TMG Methylation Essentials

2 Capsules · 60 servings · $0.47/serving

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Ingredients (5)

Folate

100%

Dose

1000 mcg DFE

Target

400–800 mcg

Form

Premium

Vitamin B12

12%

Dose

30 mcg

Target

250–5000 mcg

Form

Premium

Zinc

80%

Dose

12 mg

Target

15–30 mg

Form

Premium

Vitamin B6

20%

Dose

5.1 mg

Target

25–100 mg

Form

Budget

TMG (Trimethylglycine)

36%

Dose

900 mg

Target

2500–6000 mg

Form

—

Other Ingredients

No other ingredients listed

How to Take It

Best taken in the morning

The Vitamin B12 in it is what pulls this toward the morning. Take it with food — the zinc in it is what makes this kind of product feel nauseating on an empty stomach.

With food
Space it a couple of hours from Iron and Calcium

On the label

Take 2 capsules daily.

General guidance based on the ingredients, not a substitute for the label or your doctor.

Price Check

$27.95

$10$20

Pricier than 88% of 235 vitamin B12 supplements

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Sources & Scoring

Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).

This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.

The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.

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