Thorne Advanced Bone Support targets bone strength with a deliberately modest calcium dose backed by the cofactors that put it to work. Taken as directed — 4 capsules a day — you get 600mg of **calcium** in a well-absorbed malate form plus 2,000 IU of **vitamin D3**, both squarely in the range research supports for maintaining bone density. The calcium is kept moderate on purpose: most people already get 700–900mg from food, so this tops up the gap rather than pushing one large dose your body can't fully absorb.

Alongside the calcium you're getting 200mg of **magnesium**, a solid supplemental dose, and 6mg of **boron**, the top of its studied range for bone support. Magnesium pulls double duty here — it's required to activate vitamin D, so the calcium, D3, and magnesium work as a unit. All of these come in body-ready forms, so the numbers on the label are doses you actually absorb.

What sets this formula apart is the **folate**, **vitamin B12**, and **vitamin B6** trio. Elevated homocysteine is an independent risk factor for weaker bones and fractures, and these three are what bring it down. You're getting them in their active, ready-to-use forms — 334mcg folate, 100mcg B12, and 40mg B6 across the day — enough for that cofactor role, though folate and B12 sit just below the doses used when those vitamins are the headline ingredient.

Two things to know. Those amounts assume the full 4 capsules daily — at a single 2-capsule serving you get half, which drops several actives below their effective range, so the schedule matters. And this formula leans on boron and the B-vitamin trio rather than vitamin K2, the nutrient that steers calcium into bone instead of arteries; if K2 is a priority for you, you'd add a separate source.